Diseases that cause memory loss tend to be neurodegenerative
diseases, which are characterized by progressive deterioration within the
brain. Three common neurodegenerative memory loss diseases are Alzheimer’s
disease, Parkinson’s disease, and Huntington’s disease. Of these, Alzheimer’s
is by far the most common.
Alzheimer’s Disease
Alzheimer’s disease is a tragically common memory loss
disease; one in three people will develop Alzheimer’s before they die.
Alzheimer’s disease is a neurodegenerative disease associated with plaques and tangles
that develop in the brain. It is marked by cognitive and memory impairments
that progress in severity over time. Alzheimer’s generally arises later in
life, and its early stages are easily confused with normal memory impairment
due to aging.
Risk factors for Alzheimer’s disease include:
·
A family history of the disease
·
Mild cognitive impairment
·
Certain genetic factors
·
Existing cardiovascular disease
·
Traumatic brain injury
·
Lack of regular mental stimulation and low level
of education
As you grow older, you become increasingly more likely to
develop the symptoms of Alzheimer’s. One in nine people age 65 and older have
Alzheimer’s disease; among people 85 and older, one in three has Alzheimer’s. Statistically,
women are more likely to have Alzheimer’s than men; however, this may have to
do with the fact that women generally tend to live longer.
Parkinson’s Disease
Parkinson’s Disease is a neurodegenerative disorder
characterized by the death of dopamine-generating cells in a region of the
brain called the substantia nigra. The earliest and most obvious symptoms of
Parkinson’s disease are motor symptoms such as shaking and rigidity, but
Parkinson’s is also among the most well-known memory loss diseases and is
likely to affect a person’s ability to recall learned information.
The cause or causes of Parkinson’s disease are not yet
completely known, although evidence suggests it has a heritable genetic
component.
As many as one million Americans have Parkinson’s disease.
Worldwide, there are between seven and ten million people with this disease.
Risk factors for Parkinson’s disease include:
·
Advanced age
·
Family history of Parkinson’s
·
In women, declining estrogen levels
·
Exposure to environmental toxins, such as in the
course of agricultural work
·
Genetic factors
·
Low levels of Vitamin B Folate
·
Head trauma
Huntington ’s Disease
Huntington’s disease is a neurodegenerative disease that
affects muscle coordination and leads to cognitive decline. It can impair a
range of memory functions, including long-term memory, short-term memory,
episodic memory, and procedural memory. Huntington’s disease is more common in
people of Western European descent than those of African or Asian descent and
can affect both women and men. Huntington’s disease affects an estimated three to
seven out of every 100,000 people of European descent.
Unlike Alzheimer’s and Parkinson’s, Huntington’s disease is
caused by a known genetic factor, the dominant form of a gene called huntingtin. Because this gene is
autosomal dominant, only one parent has to have the dominant allele of the gene
for a child to inherit the disease.
Three prevalent memory loss diseases are Alzheimer’s
disease, Parkinson’s disease, and Huntington’s disease. Huntington’s disease is
caused by a dominant allele in a known gene, whereas the causes of Alzheimer’s
and Parkinson’s are less understood. Alzheimer’s is by far the most prevalent
of these diseases, and is the most likely to affect a given individual.
Depending on how long you live, the chances are that you will eventually
develop some degree of Alzheimer’s.
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